inos inhibitor 1400 w Search Results


inos inhibitor (1400 w)  (Cayman Chemical)
90
Cayman Chemical inos inhibitor (1400 w)
Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, <t>iNOS</t> [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.
Inos Inhibitor (1400 W), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/inos+inhibitor+1400+w/pmc07842273-41-1-10?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
inos inhibitor (1400 w) - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
inos selective inhibitor 1400 w  (Microm International GmbH)
90
Microm International GmbH inos selective inhibitor 1400 w
Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, <t>iNOS</t> [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.
Inos Selective Inhibitor 1400 W, supplied by Microm International GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/inos+inhibitor+1400+w/pmc04162543-103-8-14?v=Microm+International+GmbH
Average 90 stars, based on 1 article reviews
inos selective inhibitor 1400 w - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
inos inhibitor n-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide 1400 w  (Cayman Chemical)
90
Cayman Chemical inos inhibitor n-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide 1400 w
Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, <t>iNOS</t> [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.
Inos Inhibitor N [[3 (Aminomethyl)phenyl]Methyl] Ethanimidamide 1400 W, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/inos+inhibitor+1400+w/pmc04995052-80-2-6?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
inos inhibitor n-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide 1400 w - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
inos-inhibitor 1400 w  (Merck KGaA)
90
Merck KGaA inos-inhibitor 1400 w
Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, <t>iNOS</t> [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.
Inos Inhibitor 1400 W, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/inos+inhibitor+1400+w/pmc08145164-95-10-13?v=Merck+KGaA
Average 90 stars, based on 1 article reviews
inos-inhibitor 1400 w - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
selective inos inhibitor n-(3-(aminomethyl) benzyl)acetamidine (1400 w)  (Cayman Chemical)
90
Cayman Chemical selective inos inhibitor n-(3-(aminomethyl) benzyl)acetamidine (1400 w)
Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, <t>iNOS</t> [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.
Selective Inos Inhibitor N (3 (Aminomethyl) Benzyl)acetamidine (1400 W), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/inos+inhibitor+1400+w/pm26362859-88-17-43?v=Cayman+Chemical
Average 90 stars, based on 1 article reviews
selective inos inhibitor n-(3-(aminomethyl) benzyl)acetamidine (1400 w) - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier
inos inhibitor 1400w dihydrochloride  (Adipogen)
86
Adipogen inos inhibitor 1400w dihydrochloride
Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, <t>iNOS</t> [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.
Inos Inhibitor 1400w Dihydrochloride, supplied by Adipogen, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/inos+inhibitor+1400+w/pm41494606-79-1-6?v=Adipogen
Average 86 stars, based on 1 article reviews
inos inhibitor 1400w dihydrochloride - by Bioz Stars, 2026-07
86/100 stars
  Buy from Supplier

Image Search Results


Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, iNOS [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.

Journal: Biochemical pharmacology

Article Title: Correction of arginine metabolism with sepiapterin—the precursor of nitric oxide synthase cofactor BH 4 —induces immunostimulatory-shift of breast cancer

doi: 10.1016/j.bcp.2020.113887

Figure Lengend Snippet: Sepiapterin induces conversion of M2-type macrophages to M1-type macrophages in vitro . A) (Left) THP-1 human macrophages (M0) were in vitro -polarized to M1-type (by LPS + INFγ) or M2-type (by IL4 + IL13). M2-type macrophages were further treated with LPS (1 mg/ml, positive control) or sepiapterin (SEP, 100 μM) to test for their conversion to M1-type. M1 marker (red, iNOS [NOS2]); M2 marker (green, CD163). Scale bars: 50 μm. (Right) Quantification of the intensity of NOS2 or CD163 signal per cell. Error bars: ± SEM. ***, p-value < 0.001. B) (Left top) Western blot analysis of THP-1 macrophages in M0, M1 or M2 states and treated with vehicle or SEP as in A). (Right) The blots were analyzed for the expression of STAT1, p-STAT1 (p-Y701), IL-12, IL-10, CD163 or STAT3. β-actin (ACTB1) was used as the internal loading control. The intensity of each blot was quantified, normalized against ACTB1 signal and shown as the fold difference with respect to M0. Error bars: ± SEM. ***, p-value < 0.001, **, p-value < 0.005, and *, p-value < 0.05.

Article Snippet: For iNOS inhibition, iNOS inhibitor (1400 W) was obtained from Cayman Chemical (Ann Arbor, MI, USA) and used at 50 and 100 μM for 2 days [ ].

Techniques: In Vitro, Positive Control, Marker, Western Blot, Expressing, Control